GLOBAL DOWN SYNDROME FOUNDATION

DENVER, CO, 80206-5203 (720) 548-5618 Est. 2009 EIN 26-4431001
E12— Health Care Form 990 501(c)(3)
www.globaldownsyndrome.org

Mission

TO SIGNIFICANTLY IMPROVE THE LIVES OF PEOPLE WITH DOWN SYNDROME THROUGH RESEARCH, MEDICAL CARE, EDUCATION AND ADVOCACY. AN IMPORTANT PART OF THIS MISSION IS TO SUPPORT THE GLOBAL AFFILIATE ORGANIZATIONS THAT WE HELPED ESTABLISH AND CONTINUE TO FUNDRAISE FOR. GLOBAL AND OUR AFFILIATES WORK TOGETHER TO ELONGATE LIFE AND DRAMATICALLY IMPROVE HEALTH OUTCOMES TO ENSURE PEOPLE WITH THE CONDITION CAN REACH THEIR TRUE POTENTIAL. GLOBAL AFFILIATES INCLUDE: CRNIC INSTITUTE FOR DOWN SYNDROME, ALZHEIMER'S & COGNITION CENTER, SIE CENTER FOR DOWN SYNDROME, AND GLOBAL ADULT CLINIC. ANOTHER IMPORTANT PART OF OUR MISSION IS TO ENGAGE IN GOVERNMENT ADVOCACY THAT LEADS TO TRANSFORMATIVE INCREASES IN GOVERNMENT FUNDING FOR DOWN SYNDROME RESEARCH AND MEDICAL CARE WHICH IN TURN WILL CREATE A PIPELINE OF YOUNG TALENT DEDICATED TO THIS POPULATION. BECAUSE OF GLOBAL'S WORK, SCIENTISTS ARE DEVELOPING BETTER METHODS TO UNDERSTAND HOW THE TRIPLICATION LEADS TO A MUCH HIGHER INCIDENCE OF CERTAIN DISEASES (FOR EXAM

Giving Portfolio

Total Grants
56
Total Giving
$3.9M
Recipients
56
Years Active
2018 - 2024
Avg grant: $116,199 Median: $7,800

Yearly Trends

YearGrantsTotal Giving Avg GrantNewRepeat
20243$515K $172K21
20237$545K $78K34
202211$572K $52K101
20212$511K $255K11
20203$511K $170K12
201912$579K $48K102
201818$685K $38K180

Sectors Funded

Diseases & Disorders
15
Human Services
10
Education
8
Health Care
7
Unknown
1
Philanthropy & Grantmaking
1
International & Foreign Affairs
1

Top States

Colorado
13
Texas
6
Ohio
4
Tennessee
4
Indiana
3
Nebraska
3
Missouri
3
California
3
and 14 more states

Grantee Size Profile

$100K - $500K
14
Over $50M
13
$500K - $1M
12
$1M - $5M
7
Under $100K
3
$5M - $10M
1
$10M - $50M
1

Top Grantees

and 15 more grantees

Grants Awarded · 55 grants

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Financials

Total Revenue
$4,716,290
Total Expenses
$4,697,476
Net Assets
$7,285,846
25 employees 239 volunteers
From latest filing (tax period ending 2025-07-31)

Financial Health

Operating Reserve
18.6 months Healthy
Net assets / monthly expenses
Year-over-Year Change
Revenue ↑ 9.3%
Expenses ↑ 0.6%
Revenue Sources
Contributions 95.8% Earned revenue 0.1% Investment 4.1%
Expense Breakdown
Program 72.5% Management 15.4% Fundraising 12.1%

Officers & Trustees (12)

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Filing History (8 filings)

YearRevenueExpensesNet Assets
2024 Form 990$4,716,290 $4,697,476$7,285,846
2023 Form 990$4,313,796 $4,670,703$7,249,709
2022 Form 990$3,826,365 $3,562,334$7,658,555
2022 Form 990$946,045 $1,207,187$7,361,925
2021 Form 990$3,228,128 $2,669,185$7,621,868
2020 Form 990$3,586,993 $2,924,422$7,065,249
2019 Form 990$3,703,167 $3,329,779$6,404,451
2018 Form 990$4,769,092 $4,048,136$6,031,063

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EIN: 26-4431001 · Source: IRS Form 990 e-file data